Manufacturer: Focus Biomolecules
A novel small molecule survivin suppressant. YM-155 suppresses expression of survivin (a member of the IAP family) and induced apoptosis in human tumor cell lines at 10 nmol/L with little effect on other IAP or Bcl-2 family members.1 Overcomes erlotinib resistance in EGFR mutation-positive non-small cell lung cancer.2 Induces DNA damage.3 Induces an autophagy-dependent cell death in adenoid cystic carcinoma cells.4
CAS Number: 781661-94-7
Manufacturer Part Number/SKU: 10-1473-5mg-EA
Tags: Focus Biomolecules