YL-365, GPR34 antagonist, 25mg, CAS# N/A
$295.00
4-(2-(4-(Benzyloxy)phenylacetamido)-1-(3’-chloro-[1,1’-biphenyl]-4-carbonyl)piperidine-4-carboxylic acid Purity: >98% by HPLC NMR (Conforms) Store -20°C Ship RT (1 per EA )
Manufacturer: Focus Biomolecules
SKU
10-3988-25mg-EA
YL-365, GPR34 antagonist, 25mg, CAS# N/A is available to buy in increments of 1
Product Details
Download Details and SpecificationsYL-365 is a potent (IC50 = 17 nM) and selective antagonist of GPR34, a GPCR for lysophosphatidylserine.1 GPR34 is highly expressed in various immune cells and has been implicated in several types of cancer.2 YL-365 showed no activity against various other GPCRs as well as a panel of 378 kinases. It alleviated hyperalgesia in a mouse model of neuropathic pain via downregulation of iNOS in M1 microglia without any toxicity.
Manufacturer Part Number/SKU: 10-3988-25mg-EA
Tags: Focus Biomolecules