XMU-MP-1, Potent and selective MST1/2 kinase inhibitor, 25mg, CAS# 2061980-01-4
$275.00
4-[(6,10-Dihydro-5,10-dimethyl-6-oxo-5H-pyrimido[5,4-b]thieno[3,2-e]diazepin-2-yl)amino]benzenesulfonamide Purity: >98% by HPLC Purity: NMR (Conforms) Store -20°C Ship RT (1 per EA )
Manufacturer: Focus Biomolecules
SKU
10-4294-25mg-EA
XMU-MP-1, Potent and selective MST1/2 kinase inhibitor, 25mg, CAS# 2061980-01-4 is available to buy in increments of 1
Product Details
Download Details and SpecificationsXMU-MP-1 is a potent, reversible, and selective inhibitor of the HIPPO pathway kinases MST1 and MST2 (IC50s = 71 nM and 38 nM respectively).1 It promoted liver repair/regeneration in mice and attenuated acetaminophen-induced liver injury. In a subarachnoid hemorrhage mouse model, XMU-MP-1 alleviated neurological deficits, brain edema, neuroinflammation, and white matter injury.2 XMU-MP-1 was also cardioprotective in mice with transverse aortic constriction3 and against ischemia/reperfusion injury4.
CAS Number: 2061980-01-4
Manufacturer Part Number/SKU: 10-4294-25mg-EA
Tags: Focus Biomolecules