Wnt-C59, Porcupine inhibitor, 5mg, CAS# 1243243-89-1
$50.00
4-(2-Methyl-4-pyridinyl)-N-[4-(3-pyridinyl)phenyl]benzeneacetamide Purity: >98% by HPLC NMR (Conforms) Store -20°C Ship RT (1 per EA )
Manufacturer: Focus Biomolecules
SKU
10-4605-5mg-EA
Wnt-C59, Porcupine inhibitor, 5mg, CAS# 1243243-89-1 is available to buy in increments of 1
Product Details
Download Details and SpecificationsWnt-C59 is a potent (IC50 = 74 pmol/L) inhibitor of Porcupine (PORCN), a Wnt-acyltransferase. Blockage of Wnt-acyltransferase prevents secretion of all Wnt isoforms. It was able to block progression of mammary tumors in MMTV-WNT1 transgenic mice.1 Wnt-C59 strongly inhibited the growth of intestinal neoplasia in RZ-mutant mice. Wnt-C59 was able to efficiently differentiate pluripotent stem cells into cortical neurons (CTIP2+/COUP-TF1). Wnt-C59 was also able to dramatically attenuate kidney fibrosis via inhibition of collagen mRNA expression and expression of inflammatory cytokines.
CAS Number: 1243243-89-1
Manufacturer Part Number/SKU: 10-4605-5mg-EA
Tags: Focus Biomolecules