Withaferin A, NFκB and angiogenesis inhibitor, 1mg, CAS# 5119-48-2

Withaferin A, NFκB and angiogenesis inhibitor, 1mg, CAS# 5119-48-2

Wortmannin, PI3K inhibitor, 5mg, CAS# 19545-26-7

Wortmannin, PI3K inhibitor, 5mg, CAS# 19545-26-7

Withaferin_A, NFκB and angiogenesis inhibitor, 5mg, CAS# 5119-48-2

$200.00
(4ß Purity: 5ß Purity: 6ß Purity: 22R)-5,6-Epoxy-4,22,27-trihydroxy-1-oxoergosta-2,24-dien-26-oic acid d-lactone Purity: 99% by HPLC Purity: NMR (Conforms) Store -20°C Ship RT (1 per EA )

Manufacturer: Focus Biomolecules

SKU
10-2114-5mg-EA
Withaferin_A, NFκB and angiogenesis inhibitor, 5mg, CAS# 5119-48-2 is available to buy in increments of 1

Product Details

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Displays potent antiangiogenesis activity inhibiting endothelial cell sprouting in vitro (IC50 = 12 nM) and in vivo.1 Potently inhibits NF-κB activation by preventing TNFα-induced activation of IKKβ.2 Covalently binds to the intermediate filament protein, vimentin3 inducing its disassembly and serine 56 phosphorylation4. Inhibits reactive gliosis and blocks TNFα-mediated neuronal apoptosis in in vivo models.5

CAS Number: 5119-48-2

Manufacturer Part Number/SKU: 10-2114-5mg-EA

Tags: Focus Biomolecules