Manufacturer: Focus Biomolecules
A potent and selective inhibitor of p38 MAP kinases, p38a MAPK and p38b (KD = 3.7 and 17 nM respectively).1 Inhibits IL-6, IL-1b and TNFa production in LPS-primed blood.1 Inhibits p38 in platelets stimulated by thrombin, collagen or thromboxane agonist U-46619 at 1 mM.2 Provides only modest clinical efficacy in rheumatoid arthritis.3,4 Delays platelet lesions and leads to better maintenance of stored platelets.5
CAS Number: 745833-23-2
Manufacturer Part Number/SKU: 10-2181-50mg-EA
Tags: Focus Biomolecules