VX-702, p38α MAP kinase inhibitor, 10mg, CAS# 745833-23-2
$40.00
6-[(Aminocarbonyl)(2,6-difluorophenyl)amino]-2-(2,4-difluorophenyl)-3-pyridinecarboxamide Purity: 98% by HPLC NMR (Conforms) Store -20°C Ship RT (1 per EA )
Manufacturer: Focus Biomolecules
SKU
10-2181-10mg-EA
VX-702, p38α MAP kinase inhibitor, 10mg, CAS# 745833-23-2 is available to buy in increments of 1
Product Details
Download Details and SpecificationsA potent and selective inhibitor of p38 MAP kinases, p38a MAPK and p38b (KD = 3.7 and 17 nM respectively).1 Inhibits IL-6, IL-1b and TNFa production in LPS-primed blood.1 Inhibits p38 in platelets stimulated by thrombin, collagen or thromboxane agonist U-46619 at 1 mM.2 Provides only modest clinical efficacy in rheumatoid arthritis.3,4 Delays platelet lesions and leads to better maintenance of stored platelets.5
CAS Number: 745833-23-2
Manufacturer Part Number/SKU: 10-2181-10mg-EA
Tags: Focus Biomolecules