VU0134992, Kir4.1 blocker, 5mg, CAS# 755002-90-5
$45.00
2-(2-Bromo-4-propan-2-yl)phenoxy)-N-(2,2,6,6-tetramethlpiperidin-4-yl)acetamide Purity: 98% by TLC NMR (Conforms) Store -20°C Ship RT (1 per EA )
Manufacturer: Focus Biomolecules
SKU
10-4651-5mg-EA
VU0134992, Kir4.1 blocker, 5mg, CAS# 755002-90-5 is available to buy in increments of 1
Product Details
Download Details and SpecificationsVU0134992 is a blocker of the inward rectifier potassium channel Kir4.1 (IC50 = 970 nM).1 It also inhibits Kir3.1/3.2, Kir3.1/3.4, and Kir4.2 with similar potency. VU0134992 induced diuresis, natriuresis, and kaliuresis in Sprague-Dawley rats suggesting therapeutic blood pressure lowering potential. It reduced polymyxin-induced nephrotoxicity in cell culture and mouse explant kidney tissue.2
CAS Number: 755002-90-5
Manufacturer Part Number/SKU: 10-4651-5mg-EA
Tags: Focus Biomolecules