Vorasidenib, Isocitrate dehydrogenase (IDH) 1/2 inhibitor, 25mg, CAS# 1644545-52-7
$280.00
6-(6-Chloropyridin-2-yl)-2-N,4-N-bis[(2R)-1,1,1-trifluoropropan-2-yl]-1,3,5-triazine-2,4-diamine Purity: >98% by HPLC NMR (Conforms) Store -20°C Ship RT (1 per EA )
Manufacturer: Focus Biomolecules
SKU
10-4659-25mg-EA
Vorasidenib, Isocitrate dehydrogenase (IDH) 1/2 inhibitor, 25mg, CAS# 1644545-52-7 is available to buy in increments of 1
Product Details
Download Details and SpecificationsVorasidenib is a highly potent (IC50's = 7 nM IDH2-R140Q, 0.6 nM IDH1-R132H/WT, and 0.25 nM Neurosphere TS603 IDH1-R132H), selective, and brain-penetrant inhibitor of mutant isocitrate dehydrogenase 1 and 2 (IDH1/2).1 It led to >97% inhibition of 2-hydroxyglutarate production in mIDH1 glioma tissue. Vorasidenib significantly improved progression-free survival and delayed time to next intervention in a phase 3 glioma trial.2
CAS Number: 1644545-52-7
Manufacturer Part Number/SKU: 10-4659-25mg-EA
Tags: Focus Biomolecules