Manufacturer: Focus Biomolecules
Phosphodiesterase PDE1 inhibitor (IC50=21 μM)1. Also blocks voltage-gated Na+ channels, IC50=44.2 μM (potency similar to phenytoin), a mechanism which may contribute to its neuroprotective and anticonvulsant activity2. It reduces inflammatory IL-1β and TNF-α expression in rat hippocampus3. Displays beneficial effects in a rat model of cerebral ischemia-reperfusion injury4. Exerts neuroprotective effects by suppressing microglial inflammation5.
CAS Number: 42971-09-05
Manufacturer Part Number/SKU: 10-1126-50mg-EA
Tags: Focus Biomolecules