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Verteporfin, YAP inhibitor, 5mg, CAS# 129497-78-5

$75.00
(4R,4aS)-18-Ethenyl-4,4a-dihydro-3,4-bis(methoxycarbonyl)-4a,8,14,19-tetramethyl-24H,26H-benzo[b]porphine-9,13-dipropanoic acid monomethyl ester Purity: 98% by TLC NMR (Conforms) Store -20°C Ship RT (1 per EA )

Manufacturer: Focus Biomolecules

SKU
10-3487-5mg-EA
Verteporfin, YAP inhibitor, 5mg, CAS# 129497-78-5 is available to buy in increments of 1

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Verteporfin inhibits transcription by YAP/TAZ, IC50 = 2.5 µM, (via disruption of YAP-TEAD interaction) inhibiting autophagy and halting proliferation of cancer and cancer stem cell lines.1,2 Inhibits autophagosome formation.3 Reverses differentiation of Src-overexpressing embryonic stem cells.4 May be used to ablate unwanted neovasculature in the eye, esophageal mucosa, and elsewhere using light to create damaging free radicals.5

CAS Number: 129497-78-5

Manufacturer Part Number/SKU: 10-3487-5mg-EA

Tags: Focus Biomolecules