Vatalanib 2HCl, VEGFRK inhibitor, 10mg, CAS# 212141-51-0
$50.00
N-(4-Chlorophenyl)-4-(4-pyridinylmethyl)-1-phthalazinamine dihydrochloride Purity: 98% by TLC Purity: NMR (Conforms) Store -20°C Ship RT (1 per EA )
Manufacturer: Focus Biomolecules
SKU
10-2183-10mg-EA
Vatalanib 2HCl, VEGFRK inhibitor, 10mg, CAS# 212141-51-0 is available to buy in increments of 1
Product Details
Download Details and SpecificationsPotent, selective inhibitor of the VEGFR tyrosine kinases VEGFR-1 (Flt-1, IC50 = 77 nM) and VEGFR-2 (FLK-1/KDR, IC50 = 37 nM)1. Weaker inhibitor of other tyrosine kinases including PDGFR-β (IC50 = 580 nM), c-KIT (IC50 = 730 nM), FLT-4 (IC50 = 660 nM) and c-FMS (IC50 = 1.4 µM). Inactive against the EGFR, c-SRC, v-ABL, and protein kinase Cα (IC50 > 10 µM). Inhibits the growth of multiple myeloma cells in the bone marrow microenvironment2.
CAS Number: 212141-51-0
Manufacturer Part Number/SKU: 10-2183-10mg-EA
Tags: Focus Biomolecules