UNC-2170_HCl, Methyl-lysine binding protein inhibitor, 25mg, CAS# 1648707-58-7
$360.00
3-Bromo-N-(3-(tert-butylamino)propyl)benzamide Purity: hydrochloride Purity: 98% by TLC Purity: NMR (Conforms) Store -20°C Ship RT (1 per EA )
Manufacturer: Focus Biomolecules
SKU
10-1558-25mg-EA
UNC-2170_HCl, Methyl-lysine binding protein inhibitor, 25mg, CAS# 1648707-58-7 is available to buy in increments of 1
Product Details
Download Details and SpecificationsThe DNA damage response protein 53BP1 utilizes its tandem tudor domain to recognize dimethylated lysine 20 on histone (H4K20me2), a modification associated with double-strand DNA breaks. UNC-2170, identified by screening, was found to be a μM ligand for 53BP1 which also demonstrated at least 17-fold selectivity for 53BP1 over other methyl-lysine binding proteins. The compound functions as a 53BP1 antagonist in cell lysates and suppresses class switch recombination in whole cells, a process requiring a functioning 53BP1 tudor domain.1
CAS Number: 1648707-58-7
Manufacturer Part Number/SKU: 10-1558-25mg-EA
Tags: Focus Biomolecules