Manufacturer: Focus Biomolecules
Possesses potent immunosuppressive and anti-inflammatory activity. Irreversibly inhibits eukaryotic transcription via covalent binding to XPB, a subunit of the transcription factor TFIIH.1 Blocks transactivation of NFκB.2 Exhibits potent antiproliferative activity in 60 cancer cell lines (average IC50 = 12 nM) and synergizes with other anticancer agents.3 Inhibits the inflammatory response and remarkably decreases production of TNF-α, IL-1β and IL-6 in a rat model of rheumatoid arthritis.4
CAS Number: 38748-32-2
Manufacturer Part Number/SKU: 10-2631-5mg-EA
Tags: Focus Biomolecules