TPCA-1, Selective inhibitor of IκB kinase 2 (IKK2), 5mg, CAS# 507475-17-4
$70.00
2-[(Aminocarbonyl)amino]-5-(4-fluorophenyl)-3-thiophenecarboxamide Purity: 98% by TLC NMR (Conforms) Store -20°C Ship RT (1 per EA )
Manufacturer: Focus Biomolecules
SKU
10-5571-5mg-EA
TPCA-1, Selective inhibitor of IκB kinase 2 (IKK2), 5mg, CAS# 507475-17-4 is available to buy in increments of 1
Product Details
Download Details and SpecificationsSelective inhibitor of IκB kinase 2 (IKK2) (IC50 = 17.9 nM).1 Inhibits production of pro-inflammatory cytokines in arthritis and other animal models of inflammation.1,2 Also attenuates NLRP3 inflammasome activation in THP-1 myeloid cells, and suppresses IL1β-induced proliferation, migration, and invasion of HeLa cells.3,4 Continuous exposure to TPCA-1 promotes expansion of hematopoietic stem/progenitor cells (HSPCs) via improved glycolysis and limited ROS production.5
CAS Number: 507475-17-4
Manufacturer Part Number/SKU: 10-5571-5mg-EA
Tags: Focus Biomolecules