Manufacturer: Focus Biomolecules
Potent and selective ATP-competitive mTOR inhibitor, IC50=2 and 10 nM for mTORC1 and mTORC2 respectively.1,2 Active in vivo at inhibition of mTOR-mediated effects in mice (20 mg/kg).2 Induces autophagy.3 Torin 1-mediated enhancement of TFEB-mediated autophagy alleviates neuronal death in oxidative stress-induced disease models.4 Downregulates NGF expression in RSC96 cells.5
CAS Number: 1222998-36-8
Manufacturer Part Number/SKU: 10-3013-25mg-EA
Tags: Focus Biomolecules