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Torin_1, mTOR inhibitor, 25mg, CAS# 1222998-36-8

$280.00
1-[4-[4-(1-oxopropyl)-1-piperazinyl]-3-(trifluoromethyl)phenyl]-9-(3-quinolinyl)-benzo[h]-1,6-naphthyridin-2(1H)-one Purity: 98% by HPLC Purity: NMR (Conforms) Store -20°C Ship RT (1 per EA )

Manufacturer: Focus Biomolecules

SKU
10-3013-25mg-EA
Torin_1, mTOR inhibitor, 25mg, CAS# 1222998-36-8 is available to buy in increments of 1

Product Details

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Potent and selective ATP-competitive mTOR inhibitor, IC50=2 and 10 nM for mTORC1 and mTORC2 respectively.1,2 Active in vivo at inhibition of mTOR-mediated effects in mice (20 mg/kg).2 Induces autophagy.3 Torin 1-mediated enhancement of TFEB-mediated autophagy alleviates neuronal death in oxidative stress-induced disease models.4 Downregulates NGF expression in RSC96 cells.5

CAS Number: 1222998-36-8

Manufacturer Part Number/SKU: 10-3013-25mg-EA

Tags: Focus Biomolecules