Tolcapone, COMT inhibitor; TTR aggregation inhibitor, 50mg, CAS# 134308-13-7
$200.00
(3,4-Dihydroxy-5-nitrophenyl)(4-methylphenyl)methanone Purity: 98% by TLC Purity: NMR (Conforms) Store -20°C Ship RT (1 per EA )
Manufacturer: Focus Biomolecules
SKU
10-3075-50mg-EA
Tolcapone, COMT inhibitor; TTR aggregation inhibitor, 50mg, CAS# 134308-13-7 is available to buy in increments of 1
Product Details
Download Details and SpecificationsCatechol O-methyltransferase inhibitor (COMT), inhibiting both brain and peripheral enzymes.1 Potent inhibitor of alpha-synuclein and beta-amyloid oligomerization and fibrillogenesis protecting against extracellular toxicity.2 Binds to transthyretin (TTR) with high affinity (21 to 58 nM) and inhibits TTR aggregation in human plasma and prevents TTR-induced cytotoxicity in vitro. Stabilizes TTR in mice and humans in vivo.3 Inhibits O-methylation of exogenous polyphenols such as EGCG.4 Cell permeable. Orally bioavailable
CAS Number: 134308-13-7
Manufacturer Part Number/SKU: 10-3075-50mg-EA
Tags: Focus Biomolecules