TH1760, NUDT15 inhibitor, 25mg, CAS# 2567914-01-4
$220.00
6-[4-(1H-Indole-5-carbonyl)piperazin-1-yl]sulfonyl-3H-1,3-benzoxazol-2-one Purity: 98% by TLC Purity: NMR (Conforms) Store -20°C Ship RT (1 per EA )
Manufacturer: Focus Biomolecules
SKU
10-4624-25mg-EA
TH1760, NUDT15 inhibitor, 25mg, CAS# 2567914-01-4 is available to buy in increments of 1
Product Details
Download Details and SpecificationsPotent inhibitor (IC50 = 25 nM dGTP hydrolysis; 57 nM 6-thio-dGTP hydrolysis) of the NUDIX hydrolase NUDT15, an important enzyme involved in the hydrolysis thiopurine chemotherapeutics. It was selective against other human NUDIX proteins as well as a panel of 44 kinases and the Eurofins Cerep SafetyScreen44 panel. It was active in AML cell lines HL-60 and NB4 as well as HCT116 3-6 colorectal carcinoma cells and 697 B-ALL cells.
CAS Number: 2567914-01-4
Manufacturer Part Number/SKU: 10-4624-25mg-EA
Tags: Focus Biomolecules