TGX-221, Potent and selective PI3Kß inhibitor, 25mg, CAS# 663619-89-4

TGX-221, Potent and selective PI3Kß inhibitor, 25mg, CAS# 663619-89-4

Fruquintinib, VEGFR kinase inhibitor, 5mg, CAS# 1194506-26-7

Fruquintinib, VEGFR kinase inhibitor, 5mg, CAS# 1194506-26-7

TGX-221, Potent and selective PI3Kß inhibitor, 5mg, CAS# 663619-89-4

$55.00
9-(1-Anilinoethyl)-7-methyl-2-morpholino-4-ylpyrido[1,2-a]pyrimidin-4-one Purity: 98% by HPLC NMR (Conforms) Store -20°C Ship RT (1 per EA )

Manufacturer: Focus Biomolecules

SKU
10-4783-5mg-EA
TGX-221, Potent and selective PI3Kß inhibitor, 5mg, CAS# 663619-89-4 is available to buy in increments of 1

Product Details

Download Details and Specifications

TGX-221 is a potent (IC50 = 5 nM) and selective (1000-fold over p110α and p110γ) inhibitor of PI3-kinase isoform p110ß.1 Displays anti-thrombotic activity without affecting bleeding time.1,2 It significantly inhibited tumorigenesis in VHL, SETD2, PTEN, and CDKN2A mutated clear cell renal cell carcinoma.3 TGX-221 induced apoptosis in glioblastoma cells and inhibited cell migration and invasion.4

CAS Number: 663619-89-4

Manufacturer Part Number/SKU: 10-4783-5mg-EA

Tags: Focus Biomolecules