Telaprevir, Hepatitis C protease inhibitor, 25mg, CAS# 402957-28-2
$150.00
(3S,3aS,6aR)-2-[(2S)-2-[[(2S)-2-cyclohexyl-2-(pyrazine-2-carbonylamino)acetyl]amino]-3,3-dimethylbutanoyl]-N-[(3S)-1-(cyclopropylamino)-1,2-dioxohexan-3-yl]-3,3a,4,5,6,6a-hexahydro-1H-cyclopenta[c]pyrrole-3-carboxamide 98% by HPLC Store -20°C Ship RT (1 per EA )
Manufacturer: Focus Biomolecules
SKU
10-4929-25mg-EA
Telaprevir, Hepatitis C protease inhibitor, 25mg, CAS# 402957-28-2 is available to buy in increments of 1
Product Details
Download Details and SpecificationsHepatitis C NS3/4A protease inhibitor that is in clinical use for genotype 1 infections (IC50 = 354 nM genotype 1b replicon cells; IC50 = 280 nM human fetal hepatocytes infected with genotype 1a HCV-positive patient sera).1-3 It has been shown to inhibit SARS-CoV2 proteases MPro (IC50 = 15 µM)4 and 3CLPro (IC50 = 56 µM)5. Telaprevir is also an allosteric inhibitor of DnaK, the bacterial homolog of Hsp70. It enhanced the efficacy of aminoglycoside antibiotics and reduced resistance to the tuberculosis drug rifampin.6
CAS Number: 402957-28-2
Manufacturer Part Number/SKU: 10-4929-25mg-EA
Tags: Focus Biomolecules