Fasentin, Glucose uptake inhibitor, 5mg, CAS# 392721-37-8

Fasentin, Glucose uptake inhibitor, 5mg, CAS# 392721-37-8

Tafamidis, Transthyretin stabilizer, 5mg, CAS# 594839-88-0

Tafamidis, Transthyretin stabilizer, 5mg, CAS# 594839-88-0

Tafamidis, Transthyretin stabilizer, 25mg, CAS# 594839-88-0

$200.00
2-(3,5-Dichlorophenyl)-6-benzoxazolecarboxylic Purity: 98% by TLC NMR (Conforms) Store -20°C Ship RT (1 per EA )

Manufacturer: Focus Biomolecules

SKU
10-3743-25mg-EA
Tafamidis, Transthyretin stabilizer, 25mg, CAS# 594839-88-0 is available to buy in increments of 1

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A potent and selective transthyretin (TTR) kinetic stabilizer. It binds selectively and with negative cooperativity to the two normally unoccupied thyroxine binding sites of the TTR tetramer (Kd = ~2 and ~200 nM)1. Stabilizes wild-type and mutant TTR under varying conditions in vitro (EC50=2.7-3.2 mM).1 Clinically useful for the treatment of familial amyloid polyneuropathy2,3 and TTR-related cardiomyopathy4.

CAS Number: 594839-88-0

Manufacturer Part Number/SKU: 10-3743-25mg-EA

Tags: Focus Biomolecules