T0901317, LXR agonist, 10mg, CAS# 293754-55-9
$50.00
N-(2,2,2-Trifluoroethyl)-N-[4-[2,2,2-trifluoro-1-hydroxy-1-(trifluoromethyl)ethyl]phenyl]-benzenesulfonamide Purity: >98% by TLC NMR (Conforms) Store -20°C Ship RT (1 per EA )
Manufacturer: Focus Biomolecules
SKU
10-3361-10mg-EA
T0901317, LXR agonist, 10mg, CAS# 293754-55-9 is available to buy in increments of 1
Product Details
Download Details and SpecificationsPotent high affinity liver X receptor (LXRα and β) agonist, EC50~50 nM.1 Upregulates expression of ABCA1, a reverse cholesterol transporter, resulting in inhibition of cholesterol absorption. Inverse agonist at CAR.2 T0901317 was also shown to be an FXR agonist at lower potency than LXR thus appropriate controls must be employed when using this compound as a pharmacological tool.3 Decreases amyloid beta production in a mouse model of Alzheimer's disease.4 Inhibits cellular senescence in endothelial cells.5
CAS Number: 293754-55-9
Manufacturer Part Number/SKU: 10-3361-10mg-EA
Tags: Focus Biomolecules