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Swainsonine, Glycosidase inhibitor, 1mg, CAS# 72741-87-8

$80.00
(1S,2R,8R,8aR)-octahydro-1,2,8-indolizinetriol Purity: 98% by TLC NMR (Conforms) Store -20°C Ship RT (1 per EA )

Manufacturer: Focus Biomolecules

SKU
10-2674-1mg-EA
Swainsonine, Glycosidase inhibitor, 1mg, CAS# 72741-87-8 is available to buy in increments of 1

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A naturally occurring alkaloidal toxin found in locoweed. Inhibits the biosynthesis of complex glycoproteins by inhibition of Golgi mannosidase II (IC50 = 0.2 μM).1 Inhibits growth and potentiates the cytotoxic effect of taxol in hepatocellular carcinoma in vivo.2 Induces apoptosis in a variety of cell types including cerebral cortical neurons.3 Impairs adult neurogenesis and spatial learning and memory.4 Abrogation of complex glycosylation by swainsonine results in strain-and cell-specific inhibition of prion replication.5 Induces lysosomal storage disease in farm animals.6

CAS Number: 72741-87-8

Manufacturer Part Number/SKU: 10-2674-1mg-EA

Tags: Focus Biomolecules