Splitomicin, Sirt1 inhibitor, 5mg, CAS# 5690-03-9
$55.00
1,2-Dihydro-3H-naphtho[2,1-b]pyran-3-one Purity: 98% by TLC Purity: NMR (Conforms) Store RT Ship RT (1 per EA )
Manufacturer: Focus Biomolecules
SKU
10-2615-5mg-EA
Splitomicin, Sirt1 inhibitor, 5mg, CAS# 5690-03-9 is available to buy in increments of 1
Product Details
Download Details and SpecificationsInitially shown to inhibit Sir2p (the yeast Sirt1 homolog) and create a conditional phenocopy of a sir2 deletion mutant in S. cerevisiae1. Cells grown in the presence of the drug have silencing defects at telomeres, silent mating-type loci and the ribosomal DNA1. Inhibits all class III HDACs (sirtuins) and alleviates gene silencing in Fragile X mental retardation syndrome2. Reverses ischemic preconditioning-induced cardioprotection in a mouse model3.
CAS Number: 5690-03-09
Manufacturer Part Number/SKU: 10-2615-5mg-EA
Tags: Focus Biomolecules