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Spautin-1, Inhibits autophagy by inhibiting USP 10 and 13, 5mg, CAS# 1262888-28-7

$65.00
6-Fluoro-N[(4-fluorophenyl)methyl]-4-quinazolinamine Purity: 98% by TLC Purity: NMR (Conforms) Store -20°C Ship RT (1 per EA )

Manufacturer: Focus Biomolecules

SKU
10-1367-5mg-EA
Spautin-1, Inhibits autophagy by inhibiting USP 10 and 13, 5mg, CAS# 1262888-28-7 is available to buy in increments of 1

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A specific and potent autophagy inhibitor. Spautin-1 promotes the degradation of Vps34 PI3 kinase complexes by inhibiting two ubiquitin-specific proteases USP10 and USP13 which target the Beclin-1 subunit of Vps34 complexes1. Deranges dengue virion maturation2. Inhibits autophagy in a Beclin-1 independent manner in primary epithelial ovarian cancer cells3. Selectively induces cell death of mutant p53-expressing cancer cell lines under confluency4. Cell permeable.

CAS Number: 1262888-28-7

Manufacturer Part Number/SKU: 10-1367-5mg-EA

Tags: Focus Biomolecules