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SMI-4a, PIM1 inhibitor, 25mg, CAS# 438190-29-5

$170.00
5-(3-Trifluoromethylbenzylidene)thiazolidine Purity: 98% by TLC Purity: NMR (conforms) Store -20°C Ship RT (1 per EA )

Manufacturer: Focus Biomolecules

SKU
10-1359-25mg-EA
SMI-4a, PIM1 inhibitor, 25mg, CAS# 438190-29-5 is available to buy in increments of 1

Product Details

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A selective, ATP-competitive inhibitor of the Pim protein kinases (IC50 = 24 and 100 nM for Pim-1 and Pim-2 respectively). Selective over a panel of ~50 other kinases1. Induces cell cycle arrest in leukemia and prostate cancer cells2. Blocks the growth of a wide range of myeloid and lymphoid cell lines with precursor T-cell lymphoblastic leukemia/lymphoma (pre-T-LBL/T-ALL) being highly sensitive3. A useful tool for exploring the involvement of Pim in cellular signaling4. Cell permeable.

CAS Number: 438190-29-5

Manufacturer Part Number/SKU: 10-1359-25mg-EA

Tags: Focus Biomolecules