SLB1122168, Spns2 inhibitor, 25mg, CAS# 2999629-17-1
$365.00
(S)-6-Decyl-N-(pyrrolidine-3-ylmethyl)benzo[d]oxazol-2-amine hydrochloride Purity: >98% by HPLC NMR (Conforms) Store -20°C Ship RT (1 per EA )
Manufacturer: Focus Biomolecules
SKU
10-4396-25mg-EA
SLB1122168, Spns2 inhibitor, 25mg, CAS# 2999629-17-1 is available to buy in increments of 1
Product Details
Download Details and SpecificationsSLB1122168 is a potent (IC50 = 94 nM) second generation sphingosine-1-phosphate transporter Spinster Homolog 2 (Spns2) inhibitor. In vivo, it significantly reduced circulating lymphocyte counts but did not reduce plasma sphigosine-1-phosphate levels as with the first generation inhibitor SLF1081851 (Focus Cat# 10-4395). Spns2 inhibitors represent potential alternative immunomodulatory agents to S1P receptor agonists as they are able in induce lymphopenia without drastic changes to systemic S1P levels or stimulating the S1P1-5 signaling pathway.
CAS Number: 2999629-17-1
Manufacturer Part Number/SKU: 10-4396-25mg-EA
Tags: Focus Biomolecules