Manufacturer: Focus Biomolecules
Separase is a cysteine protease that triggers chromosome segregation during mitosis and is highly overexpressed in many cancers. SIC5-6 is an inhibitor of separase with no inhibition of the related protease caspase-1 in vitro. HeLa cells with dysregulated separase activity showed severe chromosome segregation defects on treatment with 30 µM SIC5-6 indicating a potential attractive new chemotherapeutic target.
CAS Number: 2410846-16-9
Manufacturer Part Number/SKU: 10-4075-10mg-EA
Tags: Focus Biomolecules