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Selinexor, CRM1/XPO1 nuclear export receptor inhibitor, 5mg, CAS# 1393477-72-9

$65.00
(Z)-3-[3-[3,5-Bis(trifluoromethyl)phenyl]-1,2,4-triazol-1-yl]-N’-pyrazin-2-ylprop-2-enehydrazide; Purity: 98% by TLC NMR (Conforms) Store -20°C Ship RT (1 per EA )

Manufacturer: Focus Biomolecules

SKU
10-4011-5mg-EA
Selinexor, CRM1/XPO1 nuclear export receptor inhibitor, 5mg, CAS# 1393477-72-9 is available to buy in increments of 1

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Selinexor is a potent inhibitor of the nuclear export receptor, chromosome region maintenance 1 (CRM1; Exportin-1 (XPO1)). It exhibited potent growth suppression in various T-cell acute lymphoblastic leukemia (T-ALL) cells (IC50's = 34-203 nM)1 and pancreatic cancer cells (IC50 ~ 150 nM)2. Selinexor is being investigated as a possible chemotherapeutic in treating multiple types of cancer.3-8 Currently in clinical trials.

CAS Number: 1393477-72-9

Manufacturer Part Number/SKU: 10-4011-5mg-EA

Tags: Focus Biomolecules