SCR7 pyrazine, CRISPR enhancer, 5mg, CAS# 14892-97-8
$70.00
2,3-Dihydro-6,7-diphenyl-2-thioxo-4(1H)-pteridinone Purity: >98% by TLC NMR (Conforms) Store -20°C Ship RT (1 per EA )
Manufacturer: Focus Biomolecules
SKU
10-3652-5mg-EA
SCR7 pyrazine, CRISPR enhancer, 5mg, CAS# 14892-97-8 is available to buy in increments of 1
Product Details
Download Details and SpecificationsSCR7 pyrazine enhances the efficiency of precise genome editing with CRISPR/Cas9 up to 19-fold via inhibition of nonhomologous end joining (NHEJ).1,2 May be employed in an optimized CRISPR/Cas9 method to target methylation in a site-specific manner enabling maintenance of gene silencing in vitro and in vivo.3 SCR7 pyrazine exhibits greater activity against DNA ligases I and III than DNA ligase IV.4 Induces cancer cell death via inhibition of NHEJ and potentiates the effect of double strand break-inducing therapeutic modalities.4,5
CAS Number: 14892-97-8
Manufacturer Part Number/SKU: 10-3652-5mg-EA
Tags: Focus Biomolecules