SB-225002, CXCR2 antagonist, 25mg, CAS# 182498-32-4
$240.00
N-(2-Bromophenyl)-N’-(2-hydroxy-4-nitrophenyl)urea Purity: 98% by HPLC Purity: NMR (Conforms) Store -20°C Ship RT (1 per EA )
Manufacturer: Focus Biomolecules
SKU
10-2850-25mg-EA
SB-225002, CXCR2 antagonist, 25mg, CAS# 182498-32-4 is available to buy in increments of 1
Product Details
Download Details and SpecificationsPotent and selective CXCR2 receptor antagonist (IC50 = 22 nM). Displays >150-fold selectivity over CXCR1 receptors.1 Induces apoptosis in both wild-type and p53-deficient ovarian cancer cells (OVCA) via p53 activation and by inducing mitotic catastrophe.2 Blocks IL-8-mediated cellular effects such as oxidative stress-induced cellular senescence3 and neutrophil chemotaxis1. Inhibits HIV replication in lymphocytes and macrophages.4 Inhibits endothelial activation and leukocyte recruitment to cerebral microvessels during neuroinflammation.5
CAS Number: 182498-32-4
Manufacturer Part Number/SKU: 10-2850-25mg-EA
Tags: Focus Biomolecules