SAG, Smoothened agonist, 1mg, CAS# 364590-63-6
$35.00
3-Chloro-N-[trans-4-(methylamino)cyclohexyl]-N-[[3-(4-pyridinyl)phenyl]methyl]-benzo[b]thiiophene-2-carboxamide dihydrochloride Purity: >98% by HPLC NMR (Conforms) Store -20°C Ship RT (1 per EA )
Manufacturer: Focus Biomolecules
SKU
10-4525-1mg-EA
SAG, Smoothened agonist, 1mg, CAS# 364590-63-6 is available to buy in increments of 1
Product Details
Download Details and SpecificationsSmoothened agonist which bind directly to SMO and can block SMO inhibition by cyclopamine. The conformation of SMO is altered by SAG binding which results in the accumulation of SMO in cilia and activated gene transcription. It should be noted that SAG inhibits hedgehog signaling at concentrations greater than 1 µM (EC50 for SMO activation is ~ 3 nM).1
CAS Number: 364590-63-6
Manufacturer Part Number/SKU: 10-4525-1mg-EA
Tags: Focus Biomolecules