Ruxolitinib, JAK inhibitor, 5mg, CAS# 941678-49-5
$65.00
ßR-Cyclopentyl-4-(7H-pyrrolo[2,3-d]pyrimidin-4-yl)-1H-pyrazole-1-propanenitrile Purity: 99% by HPLC Purity: NMR (conforms) Store -20°C Ship RT (1 per EA )
Manufacturer: Focus Biomolecules
SKU
10-4511-5mg-EA
Ruxolitinib, JAK inhibitor, 5mg, CAS# 941678-49-5 is available to buy in increments of 1
Product Details
Download Details and SpecificationsPotent and selective JAK1&2 inhibitor, IC50s=2.7, 4.5 and 322 nM forJAK1, JAK2 and JAK3 respectively.1 Blocks IL-6 signaling (IC50=281 nM) and proliferation of JAK2V617F+ Ba/F3 cells (IC50=127 nM).2 Inhibits the proinflammatory secretome of senescent cells.3 The JAK1 S646P mutant is highly sensitive to ruxolitinib.4 Clinically useful cancer chemotherapeutic.
CAS Number: 941678-49-5
Manufacturer Part Number/SKU: 10-4511-5mg-EA
Tags: Focus Biomolecules