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Rucaparib_phosphate, PARP1 inhibitor, 25mg, CAS# 459868-92-9

$280.00
8-Fluoro-1,3,4,5-tetrahydro-2-[4-[(methylamino)methyl]phenyl]-6H-pyrrolo[4,3,2-ef][2]benzazepin-6-one Purity: 98% by HPLC NMR (Conforms) Store -20°C Ship RT (1 per EA )

Manufacturer: Focus Biomolecules

SKU
10-3321-25mg-EA
Rucaparib_phosphate, PARP1 inhibitor, 25mg, CAS# 459868-92-9 is available to buy in increments of 1

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Rucaparib is a potent (Ki<5 nM) PARP1 inhibitor.1 Cytotoxic to human cancer cells or xenograft tumors with mutated or epigenetically silenced BRCA1/2.2 Demonstrates antiproliferative effects in 26 out of 39 ovarian cancer cell lines.3 Synergizes with other anticancer agents such as topotecan, carboplatin, doxorubicin, paclitaxel3 and temozolamide.4 Ameliorates the cardiotoxicity of doxorubicin.5 Recently approved for human use by the FDA.

CAS Number: 459868-92-9

Manufacturer Part Number/SKU: 10-3321-25mg-EA

Tags: Focus Biomolecules