RI-1, RAD51 inhibitor, 25mg, CAS# 415713-60-9
$208.00
3-Chloro-1-(3,4-dichlorophenyl)-4-(4-morpholinyl)-1H-pyrrole-2,5-dione Purity: 98% by TLC Purity: NMR (Conforms) Store -20°C Ship RT (1 per EA )
Manufacturer: Focus Biomolecules
SKU
10-1617-25mg-EA
RI-1, RAD51 inhibitor, 25mg, CAS# 415713-60-9 is available to buy in increments of 1
Product Details
Download Details and SpecificationsRI-1 is a potent and selective inhibitor of RAD51 (IC50 = 5-30 μM), a highly conserved protein that catalyzes DNA repair via homologous recombination.1 It specifically reduces gene conversion in human cells and stimulates single strand annealing. It covalently binds to Cys319 on the surface of RAD51 and disrupts protein-protein interaction. It potentiates the effect of DNA-damaging agents on tumor cells and is a novel tool for studying DNA repair in cells.2 Potentiates the killing of glioblastoma cells by ionizing radiation3 and alkylating drugs4.
CAS Number: 415713-60-9
Manufacturer Part Number/SKU: 10-1617-25mg-EA
Tags: Focus Biomolecules