R428, AXL inhibitor, 5mg, CAS# 1037624-75-1
$65.00
1-(3,4-Diazatricyclo[9.4.0.02,7]pentadeca-1(15),2,4,6,11,13-hexaen-5-yl)-3-N-[(7S)-7-pyrrolidin-1-yl-6,7,8,9-tetrahydro-5H-benzo[7]annulen-3-yl]-1,2,4-triazole-3,5-diamine Purity: 98% by HPLC NMR (Conforms) Store -20°C Ship RT (1 per EA )
Manufacturer: Focus Biomolecules
SKU
10-4676-5mg-EA
R428, AXL inhibitor, 5mg, CAS# 1037624-75-1 is available to buy in increments of 1
Product Details
Download Details and SpecificationsR428 (1037624-75-1) is a potent and selective inhibitor of AXL kinase (IC50 = 1.4nM).1 R428 has been shown to overcome chemotherapy resistance to various agents in multiple cancer models.2-5 AXL has been shown to suppress myeloid cell activation and function - combined AXL inhibition with R428 and PD-1 blockade showed potent synergistic antitumor effects.6,7
CAS Number: 1037624-75-1
Manufacturer Part Number/SKU: 10-4676-5mg-EA
Tags: Focus Biomolecules