R-+Etomoxir_Na, Carnitine palmitoyltransferase inhibitor, 25mg, CAS# 828934-41-4
$180.00
(R)-(+)-2-[6-(4-Chlorophenoxy)hexyl]-oxirane-2-carboxylic acid sodium salt Purity: 98% by HPLC Purity: NMR (Conforms) Store -20°C Ship RT (1 per EA )
Manufacturer: Focus Biomolecules
SKU
10-4731-25mg-EA
R-+Etomoxir_Na, Carnitine palmitoyltransferase inhibitor, 25mg, CAS# 828934-41-4 is available to buy in increments of 1
Product Details
Download Details and SpecificationsEtomoxir (828934-41-4) is an irreversible inhibitor of mitochondrial carnitine palmitoyl transferase 1 (CPT1).1 It is widely used to study fatty acid oxidation. Etomoxir has been investigated as a therapeutic agent for heart disease2, diabetes3, and cancer4,5. Use of etomoxir in concentrations greater than 5 µM induces acute production of ROS with associated evidence of severe oxidative stress in proliferating T cells indicating a loss of specificity for CTP1 at these concentrations.6 200 µM etomoxir inhibited complex I of the electron transport chain.7
CAS Number: 828934-41-4
Manufacturer Part Number/SKU: 10-4731-25mg-EA
Tags: Focus Biomolecules