PY-60, YAP Activator, 25mg, CAS# 2765218-56-0
$275.00
5-Phenyl-N-[3-(1,3-thizol-2-yl)propyl]-1,2-oxazole-3-carboxamide Purity: >98% by HPLC Purity: NMR (Conforms) Store -20°C Ship RT (1 per EA )
Manufacturer: Focus Biomolecules
SKU
10-3924-25mg-EA
PY-60, YAP Activator, 25mg, CAS# 2765218-56-0 is available to buy in increments of 1
Product Details
Download Details and SpecificationsPY-60 (2765218-56-0) activates YAP transcriptional activity (EC50 = 1.6 µM) via delocalization of annexin A2 (ANXA2) from cell membranes leading to Hippo inactivation, a key controller of YAP.1 It was able to induce serum-free expansion of MCF10A cells and epidermal keratinocytes and their precursors ex vivo and in adult mice. PY-60 promoted regenerative repair of cutaneous wounds in pig and human models by enabling a pro-proliferative transcriptional program in keratinocytes and dermal cells that accelerated re-epithelization and regranulation of the wound bed.2
CAS Number: 2765218-56-0
Manufacturer Part Number/SKU: 10-3924-25mg-EA
Tags: Focus Biomolecules