Purvalanol A, CDK inhibitor, 5mg, CAS# 212844-53-6
$50.00
(2R)-2-[[6-[(3-Chlorophenyl)amino]-9-(1-methylethyl)-9H-purin-2-yl]amino]-3-methyl-1-butanol Purity: 98% by HPLC Purity: NMR (Conforms) Store -20°C Ship RT (1 per EA )
Manufacturer: Focus Biomolecules
SKU
10-2868-5mg-EA
Purvalanol A, CDK inhibitor, 5mg, CAS# 212844-53-6 is available to buy in increments of 1
Product Details
Download Details and SpecificationsCyclin-dependent kinase inhibitor. IC50s= 4, 70, 35, 75 and 850 nM for cdc2/cyclin B, cdk2/cyclin A, cdk2/cyclin E, cdk5/p35 and cdk4/cyclin D1 and respectively.1 Reversibly arrests synchronized cells in G1 and G2 phase.2 Induces ER stress-mediated apoptosis and autophagy in colon cancer cells.3 Suppresses Src-mediated transformation by inhibiting both CDKs and c-Src.4 In cells transformed with MYC, purvalanol A rapidly down-regulates survivin expression and induces MYC-dependent apoptosis.5 Cell permeable.
CAS Number: 212844-53-6
Manufacturer Part Number/SKU: 10-2868-5mg-EA
Tags: Focus Biomolecules