PLX-4032, BRAF inhibitor, 25mg, CAS# 918504-65-1
$145.00
N-[3-[[5-(4-chlorophenyl)-1H-pyrrolo[2,3-b]pyridin-3-yl]carbonyl]-2,4-difluorophenyl]-1-propanesulfonamide Purity: 99% by HPLC Purity: NMR (Conforms) Store -20°C Ship RT (1 per EA )
Manufacturer: Focus Biomolecules
SKU
10-2928-25mg-EA
PLX-4032, BRAF inhibitor, 25mg, CAS# 918504-65-1 is available to buy in increments of 1
Product Details
Download Details and SpecificationsAn ATP-competitive inhibitor of mutant V600E/F and wild type B-Raf, IC50s=31 and 100 nM respectively.1 Induced growth inhibition, G0/G1 arrest and apoptosis in a variety of cancer cell lines, with a B-Raf mutation favoring but not guaranteeing a response.2 Inhibits the growth of B-Raf V600E-positive melanomas in vitro and in vivo.3 Treatment of patients that carry the V600E BRAF mutation resulted in complete or partial tumor regression.4
CAS Number: 918504-65-1
Manufacturer Part Number/SKU: 10-2928-25mg-EA
Tags: Focus Biomolecules