PITSTOP2, Clathrin-mediated endocystosis inhibitor, 5mg, CAS# 1332879-52-3
$60.00
N-[(5Z)-5-[(4-Bromophenyl)methylidene]-4-oxo-1,3-thiazolidin-2-ylidene]naphthalene-1-sulfonamide Purity: >98% by TLC NMR (Conforms) Store -20°C Ship RT (1 per EA )
Manufacturer: Focus Biomolecules
SKU
10-4195-5mg-EA
PITSTOP2, Clathrin-mediated endocystosis inhibitor, 5mg, CAS# 1332879-52-3 is available to buy in increments of 1
Product Details
Download Details and SpecificationsPITSTOP2 inhibits clathrin-mediated endocytosis via blockade of endocytic ligand association with the clathrin terminal domain leading to clathrin coat assembly inhibition.1 It was able to cause a collapse of the nucleocytoplasmic permeability barrier and a reduction of Importin-ß binding.2 PITSTOP2 reduced viability in HeLa cells by trapping dividing cells in metaphase through loss of mitotic spindle integrity.3
CAS Number: 1332879-52-3
Manufacturer Part Number/SKU: 10-4195-5mg-EA
Tags: Focus Biomolecules