PIT-1, PH domain antagonist, 10mg, CAS# 53501-41-0
$35.00
N-[[(3-Chloro-2-hydroxy-5-nitrophenyl)amino]thioxomethyl]benzamide Purity: 98% by TLC Purity: NMR (Conforms) Store RT Ship RT (1 per EA )
Manufacturer: Focus Biomolecules
SKU
10-1192-10mg-EA
PIT-1, PH domain antagonist, 10mg, CAS# 53501-41-0 is available to buy in increments of 1
Product Details
Download Details and SpecificationsPH domain antagonist. Specifically blocks the binding of PIP3 to the Akt pleckstrin homology domain (IC50 = 31 μM). Suppresses PI3K-PDK1-Akt-dependent phosphorylation. Induces apoptosis in PTEN-deficient U87MG glioblastoma cells (IC50 = 37 μM)1. Inhibiting the binding of PIP3 to effector PH domains is new point of intervention in the PI3K signaling network2.
CAS Number: 53501-41-0
Manufacturer Part Number/SKU: 10-1192-10mg-EA
Tags: Focus Biomolecules