Picropodophyllotoxin, IGF1R inhibitor, 25mg, CAS# 477-47-4
$320.00
(5R,5aS,8aR,9R)-5,8,8a,9-Tetrahydro¬-9-hydroxy-5-(3,4,5-trimethoxyphenyl)-furo[3',4':6,7¬]naphtho[2,3-d]-1,3-dioxol-6(5aH)-one Purity: 97% by TLC Purity: NMR (Conforms) Store RT Ship RT (1 per EA )
Manufacturer: Focus Biomolecules
SKU
10-2189-25mg-EA
Picropodophyllotoxin, IGF1R inhibitor, 25mg, CAS# 477-47-4 is available to buy in increments of 1
Product Details
Download Details and SpecificationsPotent and selective inhibitor of insulin-like growth factor 1 receptor (IGF1R) which is non-competitive with ATP1. Displays no activity at IR, EGFR, FGFR or PDGFR. Inhibits IGF1R autophosphorylation IC50 ~ 1 nM1. Displays antiproliferative activity in numerous tumor cell lines, IC50 = 0.05 - 15 mM2. Exhibits antiangiogenic activitiy3. Attenuates intimal hyperplasia after vascular injury4. Active in vivo.
CAS Number: 477-47-4
Manufacturer Part Number/SKU: 10-2189-25mg-EA
Tags: Focus Biomolecules