PI-103, PI3K, mTOR and DNA-PK inhibitor, 25mg, CAS# 371935-74-9
$240.00
3-[4-(4-morpholinyl)pyrido[3’,2’:4,5]furo[3,2-d]pyrimidin-2-yl]-phenol Purity: 98% by TLC Purity: NMR (Conforms) Store -20°C Ship RT (1 per EA )
Manufacturer: Focus Biomolecules
SKU
10-5406-25mg-EA
PI-103, PI3K, mTOR and DNA-PK inhibitor, 25mg, CAS# 371935-74-9 is available to buy in increments of 1
Product Details
Download Details and SpecificationsA potent inhibitor of PI-3 kinase, mTOR and DNA-PK, IC50 = 8, 88, 150, 48, 20, 83 and 2 nM for p110α, p110ß, p110γ, p110δ, mTORC1, mTORC2 and DNA-PK respectively.1,2 Synergizes with arsenic disulfide to eradicate AML stem cells by induction of differentiation.3 Inhibits the growth of gefitinib-resistant non-small cell lung cancer cell lines.4 Induces autophagy in drug-resistant glioma.5 Protects against a-synuclein-induced toxicity in human neurons by induction of macroautophagy.6
CAS Number: 371935-74-9
Manufacturer Part Number/SKU: 10-5406-25mg-EA
Tags: Focus Biomolecules