Phenylhexyl isothiocyanate, Chemopreventive; HDAC inhibitor; p53 reactivator, 5mg, CAS# 133920-06-6
$50.00
6-Isothiocyanatohexylbenzene Purity: >98% by TLC NMR (Conforms) Store -20°C Ship RT (1 per EA )
Manufacturer: Focus Biomolecules
SKU
10-5258-5mg-EA
Phenylhexyl isothiocyanate, Chemopreventive; HDAC inhibitor; p53 reactivator, 5mg, CAS# 133920-06-6 is available to buy in increments of 1
Product Details
Download Details and SpecificationsIsothiocyanate constituents of cruciferous vegetables are potent chemopreventive agents for carcinogen-induced cancers in rodents.1 PHITC was the most potent in a series of synthetic arylalkyl isothiocyanates at inhibition of tumorigenicity by NNK, a tobacco-derived nitrosamine, in a mouse model.2 It was also found to induce apoptosis and inhibit leukemia cell growth in vivo3 and was shown to have dual function as a histone deacetylase inhibitor and hypomethylating agent4. PHITC was also shown to restore the activity of mutant p53 and reactivate the p53 pathway in human myeloid leukemia M2 cells.5
CAS Number: 133920-06-6
Manufacturer Part Number/SKU: 10-5258-5mg-EA
Tags: Focus Biomolecules