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PF-9366, Methionine adenosyltransferase 2A inhibitor, 5mg, CAS# 72882-78-1

$60.00
2-(7-Chloro-5-phenyl)-[1,2,4]triazolo[4,3-a]quinoline-1-yl)-N,N,dimethylethanamine Purity: 98% by TLC NMr (Conforms) Store -20°C Ship RT (1 per EA )

Manufacturer: Focus Biomolecules

SKU
10-4635-5mg-EA
PF-9366, Methionine adenosyltransferase 2A inhibitor, 5mg, CAS# 72882-78-1 is available to buy in increments of 1

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PF-9366 is an allosteric inhibitor (IC50 = 420 nM) of methionine adenosyltransferase 2A (Mat2A), the primary enzyme responsible for extrahepatic synthesis of S-adenosyl-L-methionine (SAM).1 It inhibited cellular SAM production in H520 lung and Huh-7 liver cancer cells with IC50's of 1.2 µM and 225 nM respectively.

CAS Number: 72882-78-1

Manufacturer Part Number/SKU: 10-4635-5mg-EA

Tags: Focus Biomolecules