PB28 dihydrochloride, High affinity sigma 2 ligand / Anti-SARS-COV2, 5mg, CAS# 172907-03-8
$45.00
1-Cyclohexyl-4-[3-(1,2,3,4-tetrahydro-5-methoxy-1-naphthalenyl)propyl]piperazine dihydrochloride Purity: 99% by HPLC NMR (Conforms) Store -20°C Ship RT (1 per EA )
Manufacturer: Focus Biomolecules
SKU
10-4665-5mg-EA
PB28 dihydrochloride, High affinity sigma 2 ligand / Anti-SARS-COV2, 5mg, CAS# 172907-03-8 is available to buy in increments of 1
Product Details
Download Details and SpecificationsPB28 is a very potent high affinity (Ki = 5.3 nM1, 0.34 nM2) sigma 2 agonist. Selective for sigma 2 over sigma1 (approx 30-40x).1,2 PB28 inhibited cell growth in MCF7 and MCF7 ADR breast cancer cells and displayed strong synergism with doxorubicin.3 PB28 potently inhibited Kv2.1 currents in a sigma-independent manner.4 PB28 was recently found to have potent (IC50 = 280 nM) anti-SARS-CoV2 activity.5
CAS Number: 172907-03-8
Manufacturer Part Number/SKU: 10-4665-5mg-EA
Tags: Focus Biomolecules