Palbociclib, CDK4/CDK6 inhibitor, 25mg, CAS# 571190-30-2
$150.00
6-Acetyl-8-cyclopentyl-5-methyl-2-[[5-piperazin-1-yl)pyridine-2-yl]amino]-8H-pyrido[2,3-d]pyrimidin-7-one Purity: 99% by HPLC/TLC NMR (Conforms) Store -20°C Ship RT (1 per EA )
Manufacturer: Focus Biomolecules
SKU
10-4760-25mg-EA
Palbociclib, CDK4/CDK6 inhibitor, 25mg, CAS# 571190-30-2 is available to buy in increments of 1
Product Details
Download Details and SpecificationsPotent and selective inhibitor of Cdk4, IC50 = 11 nM and Cdk6, IC50 = 16 nM.1 Inhibits phosphorylation of Rb protein and cell cycle progression through G1 in primary 5T33MM cells and sensitized these cells to killing by a proteasome inhibitor (bortezomib) in mouse models.2 Induces autophagy and senescence in AGS gastric cancer cells.3 Clinically useful breast cancer agent.4 Cell cycle inhibitors boost tumor immunogenicity.5
CAS Number: 571190-30-2
Manufacturer Part Number/SKU: 10-4760-25mg-EA
Tags: Focus Biomolecules