PAC-1, Procaspase activator, 25mg, CAS# 315183-21-2
$95.00
4-(Phenylmethyl)-1-piperazineacetic acid [[2-hydroxy-3-(2-propenyl)phenyl]-methylene]hydrazide Purity: 98% by HPLC Purity: NMR (Conforms) Store -20°C Ship RT (1 per EA )
Manufacturer: Focus Biomolecules
SKU
10-2979-25mg-EA
PAC-1, Procaspase activator, 25mg, CAS# 315183-21-2 is available to buy in increments of 1
Product Details
Download Details and SpecificationsPAC-1 is a procaspase-activating compound, directly activating procaspase-3, producing caspase-3, EC50=0.22 μM.1 It is less potent at activating procaspase-7, EC50=4.5 μM. It induces apoptosis in a variety of cancer cell lines. The mechanism of activation involves sequestering inhibitory zinc ions thus allowing procaspase-3 to autoactivate.2 Sensitizes cancer cells to various chemotherapeutic agents.3
CAS Number: 315183-21-2
Manufacturer Part Number/SKU: 10-2979-25mg-EA
Tags: Focus Biomolecules