Olodanrigan, Angiotensin II type 2 receptor antagonist, 5mg, CAS# 1316755-16-4
$75.00
(S)-Benzyloxy-2-diphenylacetyl-6-methoxy-1,2,3,4-tetrahydroisoquinoline-3-carboxylic acid Purity: >98% by HPLC (NMR Conforms) Store -20°C Ship RT (1 per EA )
Manufacturer: Focus Biomolecules
SKU
10-4957-5mg-EA
Olodanrigan, Angiotensin II type 2 receptor antagonist, 5mg, CAS# 1316755-16-4 is available to buy in increments of 1
Product Details
Download Details and SpecificationsPotent (IC50 = 39.5 nM) and selective (>10,000-fold selectivity AT2R/AT1R) antagonist of the angiotensin II type 2 receptor.1 It produced dose-dependent relief of hindpaw sensitivity in a rat model of neuropathic pain1 and showed efficacy in a human trial against postherpetic neuralgia2. Olodanrigan prevented paclitaxel-associated acute pain syndrome in mice.3 It blocked visceral hypersensitivity and colonic hyperpermeability in a rat model of irritable bowel syndrome.4 It was also able to inhibit proliferation of AT2R-expressing glioblastoma spheroids and blocked their invasiveness and angiogenic capability.5
CAS Number: 1316755-16-4
Manufacturer Part Number/SKU: 10-4957-5mg-EA
Tags: Focus Biomolecules